The metabolic acidosis therapeutics market involves drugs that treat disorders caused by excessive production or inadequate removal of acids from the body. Metabolic acidosis causes the pH level of body fluids like blood to fall below the normal range of 7.35-7.45. It is commonly seen in conditions like kidney disease, diabetic ketoacidosis, uncontrolled diabetes, lactate accumulation due to shock or low oxygen levels, poisoning or overdose of aspirin or salicylates. Metabolic acidosis therapy aims to restore normal acid-base balance in the body. Traditional strategies include intravenous administration of sodium bicarbonate to raise pH levels or identifying and treating the underlying condition. However, new drug developments seek to curb acid production in specific disease contexts.
The metabolic acidosis market is estimated to be valued at USD 177.9 Mn in 2024 and is expected to reach USD 265.5 Mn by 2031, growing at a compound annual growth rate (CAGR) of 5.89% from 2024 to 2031.
Key Takeaways
Key players operating in the metabolic acidosis market include AstraZeneca, Horizon Pharma, and Takeda Pharmaceutical. These companies offer treatment products based on sodium bicarbonate and undertake drug development efforts to expand therapeutic options.
The market sees Metabolic Acidosis Market Opportunities in advancing early diagnostics to identify acidosis onset. Better screening can aid timely intervention. There is also scope for increasing awareness about complications from untreated acidosis among healthcare workers and patients.
Recent years have witnessed significant research into novel metabolic acidosis drugs targeting kidney disease and diabetic ketoacidosis. Advancements include selective compounds reducing acid generation in specific organs. Others aim to restore pH balance through new mechanisms of action.
Market drivers
A key market driver is the rising global prevalence of chronic diseases predisposing to metabolic acidosis like renal failure and uncontrolled diabetes. As per the National Kidney Foundation, over 37 million Americans suffer from chronic kidney disease. Similarly, the International Diabetes Federation estimates 9.3% of the world's adult population have diabetes. With limited treatment options currently, the need for improved acidosis management remains high.
Current Challenges in Metabolic Acidosis Market
Metabolic acidosis is associated with various diseases and disorders, and needs effective treatment options. However, the metabolic acidosis market faces few challenges. Diagnosis of underlying cause is difficult in some cases. Also, treatment plans require close monitoring to determine response and adjust therapies. Lack of awareness about metabolic acidosis among general public delays diagnosis. Further, high treatment cost is a concern for many patients. Developing cost-effective drugs and diagnostic tools could help address some challenges.
SWOT Analysis
Strength: Growing research to develop novel drugs for targeted therapy. Existing drugs offer treatment options.
Weakness: High costs associated with diagnosis and long-term management. Lack of approved drugs for some specific causes.
Opportunity: Rising acidosis cases due to chronic diseases creates demand. Developing economies present market potential.
Threats: Stringent regulations for drug approvals. Patent expiry of major drugs.
Geographical Regions
North America accounts for the largest share of the global metabolic acidosis market, both in terms of value and volume. This is attributed to high healthcare spending and growing patient population in the US.
Asia Pacific shows potential for fastest growth during the forecast period. This is due to rising income levels, improvement in diagnosis rate, and increasing government focus on healthcare sector in emerging countries like India and China. Growing patient base of metabolic disorders and improving access to healthcare infrastructure support market growth in the region.
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